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Xia, Yun MD, PhD


Staff photo

410 W 10th Ave
Columbus, OH 43210

Phone: (614) 293-8487

Email: xia.5@osu.edu

 

Current OSU Appointments

Professor-Clinical, Anesthesiology

Professor-Clinical, SBS-Physiology & Cell Biology

Physician, FGP-Anesthesiology

 

Clinical Interest

Anesthesiology

Creative Works

1. I am a director of "No Pain Labor and Delivery - Global Health Initiatives (NPLD_GHI)", a SOAP (Society for Obstetric Anesthesia and Perinatology) outreach program. This is an annual week-long educational program includes one-on-one bedside instruction, daily debriefing sessions discussing daily goals and objectives, crash cesarean delivery simulation drills, and a weekend conference along with a patient education course at each site.

NPLD-GHI was launched in China in 2008 to assist local hospitals in the establishment of self-sustaining obstetric anesthesia systems that will allow them to provide safe and effective neuraxial analgesia (NA). It also aimed to provide annual multidisciplinary visits with continual follow-up to increase collaboration among anesthesiologists, obstetricians, nurses/midwives, and neonatologists. A total of 11 bilingual documents of protocols, responsibilities, and medical records were created, and a web-based translational medical-educational-management informatics system called Baby-on-Board was designed. Additionally, four textbooks and two patient education books were written or translated and published in Chinese.

2. I developed a research curriculum for CRNA program at University of Akron in 2001 and several CRNAs completed their research requirements with me.

I worked with other research faculty in our department to develop the curriculum of research week for CA-1 residents.

I am in the process to create a curriculum for International Medicine rotation for anesthesia residents.

Advising Narrative

Giving lectures to Physiology 311 and 312 classes:

(1) The autonomic nervous system
(2) The acid--base balance

2. Tutoring students of Physiology 601and 602 classes on all aspects of physiology.

Academic Advising

1. Graduate School Representative to Ph.D. candidacy exam:
Kathleen Marie Koechlin, Public Health-410, SP/02
Jiyun Chen, College of Pharmacy, Au/03
Eunju Hurh, College of Pharmacy, Su/04
Xiaogang Pan, College of Pharmacy, Au/05

2. Advisor for SRNAs and Students:
Cardiac anomaly (coronary artery) in parturients (Chris Rosile)
Pre-eclampsia and coarctation of aorta (Dan Rittenhouse)
Hereditary hemorrhagic telangiectasia (Stephanie List)
Effects of neostigmine on intrathecal morphine induced constipation (Sue Kirchner, Rebecca Petzinger, & George Friedhoff)
Pulmonary hypertension during pregnancy (Gina Mitchell)
Effects of Zofran on intrathecal morphine induced pruritus (Jennifer Lewis)
The complexity of anesthesia for pregnant patients with spinal muscular atrophy (Angela Walters)

3. Host/Advisor for Visiting Scholars in Anesthesiology:
Tiehu Ye (Peking Union Medical College), October, 1997
Zhiyi Zuo (University of Virginia) 2004
Qingping Wu (Tongji Medical College) 2006
Qingquan Lian (Wenzhou Medical University) 2006
Hong Chao (Wenzhou Medical University) 2006
Zongze Zhang (Wuhan University),Oct 12-28, 2006
Wangning Shangguan (Wenzhou Medical University) 2010
Jun Li (Wenzhou Medical University) 2010
Rui Xia (Yangtze University) 2010
Xuemin Song (Wuhan University), Sep 1-Dec 31, 2010
Xiaowen Guo (Zhejiang Chinese Medical University) 2011
Gang Yang (Three Gorges University) 2011
Wei Zhang (Zhengzhou University) 2011
Hanbing Wang (First Foshan Hospital), Oct 1, 2011-Apr 30, 2012
Hai Lin (Wenzhou Medical University) 2012
Gaoping Luo (Wuhan Puai Hospital) 2012
Juan Zhang (Zhejiang Chinese Medical University) 2012
Quanguang Wang (Wenzhou Medical University) 2012-2013
Zhihong Lu (Fourth Military Medical University) 2013
Xuetao Yan (Shenzhen Maternal and Children Hospital), Dec 1, 2012-April 30, 2013
Chang Chen (Wuhan University), May 1-Nov 30, 2013
Xiangqing Xiong (Wenzhou Medical University) 2013
Zhi Wang (Shanxi Provincial Hospital) 2013-2014
Yingjun She (Guangzhou Maternal and Children Hospital) 2014
Jia Zhan (Wuhan University), May 1-August 30, 2014
Jiehao Sun (Wenzhou Medical University), July 1-September 30, 2014
Yunlong Zhang (Zhejiang Provincial Hospital), October 1-December 31, 2014
Xianghu He (Wuhan University), January 31-May 31, 2015
Zhijian You (Shantou University), April 5-8, 2015


4. Host International Visitors:
Wolfgang Sadee 2005
Zhongping Feng (University of Toronto) 2007
Songhe Jiang (Wenzhou Medical College) 2008
Xueqiong Zhu (Wenzhou Medical College) 2009
Xiaofeng Zheng (Wenzhou Medical College) 2009
Xiaoying Huang (Wenzhou Medical College) 2010
Huiping Li (Wenzhou Medical College) 2009
Xiubo Lu (Zhengzhou University) 2011
Hengliang Zhu (Wenzhou Medical College) 2012-2013
Duo Xu (Wenzhou Medical College) 2012-2013
Jingying Zhu (Wenzhou Medical College) 2012-2013
Xiaohua Liu (Shanghai Maternal and Children Hospital) 2012
Yudong Wang (Shanghai Maternal and Children Hospital) 2013
Fan Wang (Wenzhou Medical University) 2013
Pamela Flood (Stanford University) 2014

5. Advisor for Anesthesiology Resident Peter Wang
Efficacy of ondansetron for treatment of intrathecal morphine induced pruritus

Advisor for anesthesiology residents Eric Orindorff, Andy Shirk
Dose-effects of neostigmine in spinal anesthesia

6. Resident Advisor in the last 14-year period
Meet with residents on a regular basis throughout their residency&emsp(Diane Tran, Denicha Rankin, Nancy Alkire, Ryan Dalton, Jennifer Watson, Dheer Vyas)

7. Supervision of OSU PACU nurses during their research
PONV study presented at (1) 2012 Nursing Excellence Fair, April 30 - May 1, 2012 at Ross Heart Hospital Auditorium, Wexner Medical Center at OSU; and (2) OPANA (Ohio Post Anesthesia Nurses Association) Fall Conference, Oct. 13, 2012, at Seigel Center , Mt. Carmel East. Columbus, Ohio.

8. Advisor for OSU Medical Student
Abraham Khorasani (Med 3), December 2014

8. Supervisor for high school and college students during their clinical shadowing.

Continuing Education, Extension, and Other Courses Taught

1. Grand Rounds:
Research design and research ethics (2006)
Anesthetic consideration of obstetrical patients with thrombocytopenia (2007)
What is new in 2007 Practice Guidelines for OB Anesthesia (2008)
Epidural catheter migration (2009)
Anesthesia and GI function (2009)
Update of preeclampsia (2010)
Update of preeclampsia (2012)
Anesthetic managements of HELLP Syndrome (2012)
Failed epidural top-up for cesarean delivery (February 2013)
Sickle cell disease management in pregnancy (April 2013)
Oxytocin in obstetric anesthesia (October 24, 2013)
Anesthetic managements of an ultra-obese parturient (February 6, 2014)

2. Annual Lecture Series for anesthesiology residents and medical students:
&emspAnesthesia for patients with rare and co-existing disease
&emspThe renal system and anesthesia for urological surgery
&emspAnesthesia for Obstetrics
&emspIntroduction to Obstetrics anesthesia
&emspIntroduction to Thoracic Anesthesia

3. Monthly Lecture Series for medical students (Med3 and Med4):
OB Anesthesia
Neuroaxial Block

4. Introductory Didactic Lecture Series for New Residents:
&emspEpidural and spinal anesthesia
&emspCentroneuraxis Blocks

5. CA-1 Lecture Series:
&emspEndocrine and nutritional diseases
&emspProcedures performed outside the operating room
&emspMaternal & Fetal Physiology and Anesthesia
&emspOB anesthesia

6. CA-2 Lecture Series:
&emspManagement of anesthesia for the pregnant surgical patients
&emspPregnancy induced hypertension and HELLP Syndrome
&emsp&emspEndocrine emergencies
&emsp&emspAnesthesia for obstetrics
&emsp&emspObstetric epidurals and chronic adhesive arachnoiditis
&emsp&emspPeripartum Care of Cocaine Abusers

7. CA-2 and CA-3 Lecture Series:
&emsp&emspDifficult airway management
&emsp&emspObstetric emergencies and anesthetic management
&emsp&emspComplementary and Alternative Therapies
&emsp&emspNeuromuscular blockade
8. CA-3 Lecture Series:
Rare and co-existing diseases in anesthesia
Keywords #3
Emergency cesarean section
Risk management in anesthesia practice
Medical legal issues
Peripartum care of the cocaine abusing patient

9. OB Anesthesia Case Discussions:
&emspDaily educational discussion and weekly lectures for all the residents during their OB anesthesia rotation

10. Monthly Lecture Series for obstetric anesthesia residents
&emspUpdate of preeclampsia
&emspPerinatal hemorrhage

11. Lecture Series for Anesthesia Technicians Training:
Regional anesthesia
&emsp&emsp
12. Introduction to Research (monthly)
During the one-hour lecture and tour, residents can have some idea about the Subspecialty Clinical Tract during their residency training and the Clinician Scientist Pathway after the residency training, learn possible funding opportunity in an academic medical center. If time allows, the residents will gain knowledge in Neurogastroenterology (NG) and the Enteric Nervous System (ENS), learn the significance of NG and ENS in anesthesia practice, take a brief basic science laboratory tour, gain knowledge in basic science research organization and techniques, and gain knowledge in research design and how a research project is carried out in both basic science and clinical practice.
&emsp&emsp&emsp
13. Mock Oral Examiner for anesthesia residents

14. The Ohio State University Medical Center
Department of Obstetrics and Gynecology, RN Competency for Women and Infants:
&emspMedical Pain Management for the Obstetrical Patients
&emspAnesthesia for Labor and Delivery

15. The Region IV Perinatal Center
Obstetric anesthesia update
&emsp
16. Chinese Student and Scholar Society
Introduction to labor and delivery
Labor analgesia

17. OSU Medical Center Summer Education Program (1998)

Postdoctoral / Researcher Advising

1. Advisor for SRNAs and Students:
Cardiac anomaly (coronary artery) in parturients (Chris Rosile)
Pre-eclampsia and coarctation of aorta (Dan Rittenhouse)
Hereditary hemorrhagic telangiectasia (Stephanie List)
Effects of neostigmine on intrathecal morphine induced constipation (Sue Kirchner, Rebecca Petzinger, & George Friedhoff)
Pulmonary hypertension during pregnancy (Gina Mitchell)
Effects of Zofran on intrathecal morphine induced pruritus (Jennifer Lewis)
The complexity of anesthesia for pregnant patients with spinal muscular atrophy (Angela Walters)

2. Advisor for Anesthesiology Resident Peter Wang
Efficacy of ondansetron for treatment of intrathecal morphine induced pruritus

Advisor for anesthesiology residents Eric Orindorff, Andy Shirk
Dose-effects of neostigmine in spinal anesthesia

3. Supervision of OSU PACU nurses during their research
PONV study presented at (1) 2012 Nursing Excellence Fair, April 30 - May 1, 2012 at Ross Heart Hospital Auditorium, Wexner Medical Center at OSU; and (2) OPANA (Ohio Post Anesthesia Nurses Association) Fall Conference, Oct. 13, 2012, at Seigel Center , Mt. Carmel East. Columbus, Ohio

Master/Graduate Advising

1. Graduate School Representative to Ph.D. candidacy exam:
Kathleen Marie Koechlin, Public Health-410, SP/02
Jiyun Chen, College of Pharmacy, Au/03
Eunju Hurh, College of Pharmacy, Su/04
Xiaogang Pan, College of Pharmacy, Au/05

2. Advisor for SRNAs and Students:
Cardiac anomaly (coronary artery) in parturients (Chris Rosile)
Pre-eclampsia and coarctation of aorta (Dan Rittenhouse)
Hereditary hemorrhagic telangiectasia (Stephanie List)
Effects of neostigmine on intrathecal morphine induced constipation (Sue Kirchner, Rebecca Petzinger, & George Friedhoff)
Pulmonary hypertension during pregnancy (Gina Mitchell)
Effects of Zofran on intrathecal morphine induced pruritus (Jennifer Lewis)
The complexity of anesthesia for pregnant patients with spinal muscular atrophy (Angela Walters)

3. Advisor for Anesthesiology Resident Peter Wang
Efficacy of ondansetron for treatment of intrathecal morphine induced pruritus

Advisor for anesthesiology residents Eric Orindorff, Andy Shirk
Dose-effects of neostigmine in spinal anesthesia

4. Anesthesia Resident Advisor in the last 14-year period
Meet with residents on a regular basis throughout their residency
&emsp&emsp(Diane Tran, Denicha Rankin, Nancy Alkire, Ryan Dalton, Jennifer Watson, Dheer Vyas)

5. Supervision of OSU PACU nurses during their research
PONV study presented at (1) 2012 Nursing Excellence Fair, April 30 - May 1, 2012 at Ross Heart Hospital Auditorium, Wexner Medical Center at OSU; and (2) OPANA (Ohio Post Anesthesia Nurses Association) Fall Conference, Oct. 13, 2012, at Seigel Center , Mt. Carmel East. Columbus, Ohio

Undergraduate, Graduate, and Professional Courses Taught

A. Department of Physiology, College of Medicine, The Ohio State University

1. Giving lectures to Physiology 311 and 312 classes:

&emsp&emsp (1) The autonomic nervous system
&emsp&emsp (2) The acid--base balance

2. Tutoring students of Physiology 601and 602 classes on all aspects of physiology.

B.&emsp Department of Anesthesiology, College of Medicine, The Ohio State University

1.&emspGrand Rounds:
Research design and research ethics (2006)
Anesthetic consideration of obstetrical patients with thrombocytopenia (2007)
What is new in 2007 Practice Guidelines for OB Anesthesia (2008)
Epidural catheter migration (2009)
Anesthesia and GI function (2009)
Update of preeclampsia (2010)
Update of preeclampsia (2012)
Anesthetic managements of HELLP Syndrome (2012)
Failed epidural top-up for cesarean delivery (February 2013)
Sickle cell disease management in pregnancy (April 2013)
Oxytocin in obstetric anesthesia (October 24, 2013)
Anesthetic managements of an ultra-obese parturient (February 6)

2.&emspAnnual Lecture Series for Anesthesiology residents and medical students:
&emspAnesthesia for patients with rare and co-existing disease
&emspThe renal system and anesthesia for urological surgery
&emspAnesthesia for obstetrics
&emspIntroduction to obstetrics anesthesia
&emspIntroduction to thoracic anesthesia

3.&emspMonthly Lecture Series for Medical Students (Med3 and Med4):
OB anesthesia
Neuroaxial block

4.&emspIntroductory Didactic Lecture Series for New Residents:
&emspEpidural and spinal anesthesia
&emspCentroneuraxis Blocks

5.&emspCA-1 Lecture Series:
&emspEndocrine and nutritional diseases
&emspProcedures performed outside the operating room
&emspMaternal & fetal physiology and anesthesia
&emspOB anesthesia

6.&emspCA-2 Lecture Series:
&emspManagement of anesthesia for the pregnant surgical patients
&emspPregnancy induced hypertension and HELLP Syndrome
&emsp&emspEndocrine emergencies
&emsp&emspAnesthesia for obstetrics
&emsp&emspObstetric epidurals and chronic adhesive arachnoiditis
&emsp&emspPeripartum care of cocaine abusers

7. CA-2 and CA-3 Lecture Series:
&emsp&emspDifficult airway management
&emsp&emspObstetric emergencies and anesthetic management
&emsp&emspComplementary and alternative Therapies
&emsp&emspNeuromuscular blockade

8. CA-3 Lecture Series:
Rare and co-existing diseases in anesthesia
Keywords #3
Emergency cesarean section
Risk management in anesthesia practice
Medical legal issues
Peripartum care of the cocaine abusing patient

9. OB Anesthesia Case Discussions:
&emspDaily educational discussion and weekly lectures for all the residents during their OB anesthesia rotation

10.&emspMonthly Lecture Series for obstetric anesthesia residents
&emspUpdate of preeclampsia
&emspPerinatal hemorrhage

11.&emspLecture Series for Anesthesia Technicians Training:
Regional anesthesia
&emsp&emsp
12.&emspIntroduction to Research (monthly)
During the one-hour lecture and tour, residents can have some idea about the Subspecialty Clinical Tract during their residency training and the Clinician Scientist Pathway after the residency training, learn possible funding opportunity in an academic medical center. If time allows, the residents will gain knowledge in Neurogastroenterology (NG) and the Enteric Nervous System (ENS), learn the significance of NG and ENS in anesthesia practice, take a brief basic science laboratory tour, gain knowledge in basic science research organization and techniques, and gain knowledge in research design and how a research project is carried out in both basic science and clinical practice.

Biographical

I joined The Ohio State University College of Medicine (OSUCOM) in 1988 as a Research Associate. After receiving my Master of Science in 1991 and Doctor of Philosophy in 1993 at OSUCOM, I continued my Post-Doctoral training in the area of neuroscience for three years. Then, in 1996, I returned to clinical medicine and completed my anesthesiology residency training at The Ohio State University Wexner Medical Center (OSUWMC). Since 2000, I joined the Department of Anesthesiology at The Ohio State University as an Assistant Professor and I was promoted to the rank of Associate Professor in 2005.

With support from my department, I have fulfilled my responsibilities effectively in the areas of clinical patient care, teaching, administration, and scientific research. I have enjoyed research grants and awards, at various levels, from National Institute of Health to OSUWMC. Both my clinical and basic science research focused primarily on the effects of anesthetics on gastrointestinal function. The results of my research have been published in many peer-reviewed scientific journals. Additionally, I have been invited to give presentations at many national and international conferences, including the American Gastrointestinal Association (AGA), American Society of Anesthesiologists (ASA), Society of Obstetric Anesthesia and Perinatology (SOAP), Chinese Society of Anesthesiology (CSA), International Society of Neurogastroenterology and Motility, The American Society of Critical Care Anesthesiologists (ASCCA), and the Chinese Association of Anesthesiologists (CAA). I have also been invited to give seminars and lectures at many prestigious universities and medical institutes, such as the Mayo Clinic in Rochester, Minnesota, Harbor-UCLA in Los Angeles, California, and Peking Union Medical College in Beijing, China.

The most significant contribution I have made is to lead a SOAP out-reach program called No Pain Labor and Delivery – Global Health Initiative (NPLD-GHI) as a director. China has the highest Cesarean delivery rate in the world with less than 1% of parturients receiving neuraxial analgesia (NA) for labor. The most important role of NA is to reduce maternal/fetal morbidity and mortality. The goal of the NPLD-GHI cooperative program is to promote maternal and fetal safety during the perinatal period. More than 300 volunteers from more than 20 major medical institutions across the US have been involved in NPLD-GHI, including more than 25 OSUWMC medical personnel from anesthesiology, Ob/Gyn, and Labor & Delivery. As of 2014, we have visited 19 different Chinese hospitals. At 12 of these sites, NA rates have improved to>50% due to the outcomes of our program. Four impact studies in approximate 35,000 patients were performed in two of the hospitals showed an increase in NA of up to 60%. The results of these studies were presented at national and international anesthesia meetings documenting favorable maternal and newborn outcomes and reduction in Cesarean delivery. Data from NPLD-GHI was also used in my podium presentation at the 2013 SOAP conference on April 26, 2013 in San Juan, Puerto Rico, which was chosen as the Best Paper Presentation. NPLD-GHI has changed obstetric anesthesia and obstetrics practice in a positive way at a national level in China where there are 20 million births a year. An estimated 1.5 million parturients annually will benefit by 2018. The NPLD-GHI project has decreased Cesarean delivery in the 19 participating hospitals by 15,000 this year. Approximately 10 countries and nearly 100 media venues have reported on our activities. This intervention has brought great credit to The Ohio State University throughout Asia. (http://osumcnews.wordpress.com/2011/09/26/osumc-promotes-safe-labor-in-china/).

Furthermore, as a regional director of Global Health Education Initiatives at OSUCOM, I have participated in creating affiliations with medical institutions across China that offer OSUCOM medical students unique learning opportunities to gain exposure to a wider variety of diseases and to observe the pathogenesis of diseases, both earlier and later manifestations of many illnesses, than could actually be experienced by our medical students if they remained in the U.S. Our medical students can now observe how physicians in China utilize limited resources to provide medical care to a large population, as well as learn about traditional Chinese medicine and Chinese culture. Such experiences allow students to display their commitment to social justice, help develop credentials for career advancement, and combine learning with travel. Since 2008, OSU medical students have chosen Global Health Education electives at all four affiliated medical schools in China (Wuhan University, Xian Jiaotong University, Wenzhou Medical University, and Zhejiang Chinese Medical University), with an average of 10 medical students participating each year. In order to ensure this opportunity is always available to our medical students, I continuously maintain and nurture the relationships between the OSUCOM and our affiliated medical schools in China. (http://medicine.osu.edu/orgs/globalhealth/pages/index.aspx).

My clinical responsibilities have mainly focused on obstetric anesthesia, regional anesthesia, and thoracic anesthesia. My in depth academic experience in obstetric anesthesia and my global health education experience made me acutely aware of the dilemmas of foreign populations that did not have the options of modern pain control. Throughout the years, I have developed a keen interest in public health, in particular, maternal and fetal health in the general populations of Asia. It became clear to me that it was more suitable for me to change my academic track to one that clearly had a clinical emphasis in order to facilitate my interests in the international public health aspects of anesthesiology.

My work in China has changed the Chinese medical establishment’s approach to obstetrical anesthesia, which has impacted that country’s public health significantly, as well as the individual lives of women. In return, the Chinese medical establishment has invited OSUCOM department Chairs, Deans, and various faculty members to lecture in China and to participate in research with Chinese medical teams. A significant number of Chinese physicians have visited OSUWMC. In other words, our university’s reputation in the eyes of those who practice on the Asian continent has been significantly enhanced. We at The Ohio State University now occupy a position of academic eminence in the eyes of Chinese anesthesiologists, obstetricians, and primary care practitioners. This, combined with our placement of OSUCOM medical students at Chinese medical institutions, thereby providing significant medical and cultural learning opportunities, is consistent with the clinical excellence required in my promotion track. I have been a party to many research papers and laboratory efforts, but this “Anesthesiology” public health endeavor in which I have involved in China has made a greater impact than I could ever have imagined.

Noteworthy Graduate Narrative

I have been the Graduate School Representative to Ph.D. candidacy exam:

Kathleen Marie Koechlin, Public Health
Jiyun Chen, College of Pharmacy
Eunju Hurh, College of Pharmacy
Xiaogang Pan, College of Pharmacy

Extension Curriculum Development

I developed a research curriculum for CRNA program at University of Akron in 2001 and several CRNAs completed their research requirements with me.

I worked with other research faculty in our department to develop the curriculum of research week for CA-1 residents.

I am in the process to create a curriculum for International Medicine rotation for anesthesia residents.

Research Interest

Effects of anesthetics on gastrointestinal functions.

Professional Interests Narrative

Clinical Anesthesia. The main focus of my clinical anesthesia includes obstetric anesthesia, regional anesthesia, and thoracic anesthesia. However, I also provide anesthesia service in other areas of clinical anesthesia.

My research is focused on effects of anesthetics on gastrointestinal function.

In the basic research area, I mainly use electrophysiological technique, molecular biology, biochemistry to study the function of the enteric nervous system in both animal and human.

I also participated, as a principle investigator, in several clinical studies, including sponsored multicenter studies on treatments of opioid induced gastrointestinal dysfunctions.

Academic Advising

2013 - present Dheer Vyas, Ohio State University Wexner Medical Center.
2001 - 2002 Nancy Alkire, Ohio State University College of Medicine.
2000 - 2003 Eric Orindorff, The Ohio State University Medical Center.
2000 - 2003 Peter Wang, Ohio State University College of Medicine.
2001 - 2003 Andy Shirk, The Ohio State University Medical Center.
2000 - 2004 Ryan Dalton, The Ohio State University Medical Center.
2001 - 2004 Diane Tran, The Ohio State University Medical Center.
2006 - 2009 , The Ohio State University.
2007 - 2010 Demicha Rankin, The Ohio State University Medical Center.
2010 - 2013 Jennifer Watson, Ohio State University Wexner Medical Center.
2014 Abraham Khorasani, Ohio State University College of Medicine. Graduated 2015.
2015 Scott Diamond, The Ohio State University. Graduated 0.
2015 Thomas Wilson, The Ohio State University. Graduated 0.
2015 Mandakini Venkatramani, The Ohio State University. Graduated 0.
 

Licenses

2000 - present MD, Doctor of Medicine: State Medical Board of Ohio
2003 - present Diplomate: American Board of Anesthesiology
 

Chapters in Books

Obstetric anaesthesia.

ANESTHETIC CONSIDERATIONS IN PREECLAMPSIA

Labour analgesia

Update of Practice Guldelines of Obstetric Anesthesia in the US

Enteric Nerveous System

Anesthetic Consideration for Obstetric Patients with Thrombocytopenia and Coagulopathy

What is New in 2007 ASA Practice Guidelines for Obstetric Anesthesia

-.

OB Anesthesia

Maternal Death in the United States

Anesthetic and Obstetric Complications

ASA Practice Guidelines for Obstetric Anesthesia

Hypertensive Disorders

Maternal Death

Anesthesia for Resection of Aneterior Mediastinal Tumor

 

Clinical Services

08/01/2000 Anesthesia (The Ohio State University Wexner Medical Center)

Clinical Trials

Multicenter, Randomized, Placebo-Controlled, Double-Blinded Study of the Efficacy and Safety of Lubiprostone in patient with Opioid-induced Bowel Dysfunction (Phase 2)

A Multicenter, Double-Blinded, Randomized, Placebo-Controlled Study of Methylnaltrexone in the prevention of Post-Operative Ileus

A Multicenter, Randomized, Placebo-Controlled, Double-Blinded Study of Efficacy and Safety of Lubiprostone in patient with Opioid-induced Bowel Dysfunction (Phase 1)

 

Conferences

Dopamine D1 and D2 receptor subtypes are involved in enteric neural control of chloride and bicarbonate secretion in guinea pig duodenum

Stimulation of Spinal Afferents Evokes Slowly-Activating Excitatory Responses in Enteric Neurons in Parallel with Release of Mast Cell Proteases in Guinea Pig Ileum and Colon

 

Degrees

1983 M.D., Sun Yat-Sen University

1991 M.S., The Ohio State University

1993 Ph.D., Ohio State University College of Medicine

 

Edited Books

Evidence-Based Practice of Anesthesiology First Edition

Evidence-Based Practice of Anesthesiology Second Edition

Obstetric Anesthesia Principles and Practice

 

Editorial Activities

2009 - present Biochemical Pharmacology
2010 - present Anesthesia and Analgesia
2010 - present Chinese Journal of Clinical Anesthesia
2010 - present Chinese Medical Journal
2013 - present Journal of Inflammation Research
2013 - present Journal of Cardiaovascular Pharmacology
2014 - present Critical Care Medicine
2014 - present Translational Perioperative and Pain Medicine
 

Honors

1988 - 1993 Graduate Assistantship. The Ohio State University Medical Center.
1990 - present The Van Harreveld Memorial Award for the Year (Neuroscience Section). The American Physiological Society..
1990 - present Graduate Student Research for the Year (Gastrointestinal Section). American Physiological Society.
1993 - present AGA Student Abstract Prize. American Gastroenterological Association.
1993 - present The Bennett Research Award. Bennett Graduate Research Society.
1997 - present Research Presentation was Awarded as Top 2%. Presidential Plenary Section at Digestive Disease Week.
1999 - present First Place Award. MARC.
2000 - present First Place Award. MARC.
2001 - 2002 SEED Grant Award. The Ohio State University Medical Center.
2003 - 2008 Mentored Clinical Scientist Development Award. National Instiute of Health.
2004 - present Excellence in Community Service. Chinese Student and Scholar Society.
2004 - 2005 Davis/Bremer Medical Research Grant Award. The Ohio State University Medical Center.
2009 - present Research Poster of Distinction. Digestive Disease Week.
2013 - present Best Research Paper. Society of Obstetric Anesthesia and Perinatology.
 

Journal Articles

"Amniotic fluid embolism.." International journal of critical illness and injury science. Vol. 3, no. 1. (January 2013.): -.

 

Reference Works

January 1988 Xia Y, Lambert K, and Hofmann AF."Biliary Secretion of Ceftriaxone: Reversible Inhibition by Bile Acids Suggests a Shared Mechanism for Canalicular Transport" . : A606
January 1989 Marcus SN, Schteingart CD, Marguez ML, Xia Y, Ton-Nu H-T, Angellotti MA, Schmassman A, and Hofmann AF."Active Absorption of Conjugated Bile Acids Revisited: Accurate Kinetic Parameters and Molecular Specificity of the Ileal Transport System in the Rat" . : A320
January 1990 Xia Y, Baidan LD, Fertel RH, and Wood JD."Determination of Levels of Cyclic AMP in the Myenteric Plexus of Guinea-pig Small Intestine" . : A980
January 1991 Xia Y, Fertel RH and Wood JD."Effects of Serotonin and Selective 5-HT3 and 5-HT1P Antagonists on Levels of cAMP in Enzymatically Dissociated Ganglia from Guinea-pig Small Intestine" . : A848
January 1992 Xia Y, Fertel RH, and Wood JD."Histamine2 Receptors Stimulate cAMP Production in Enteric Nervous System of Guinea-pig Small Intestine" . : A766
January 1993 Xia Y, Christofi FL, Fertel RH, and Wood JD."Interactions of Inhibitory Adenosine A1 Receptors, Mediators of Slow Synaptic Excitation (Slow EPSP) and Adenylate Cyclase in the Myenteric Plexus of Guinea-pig Small Intestine." . : A1068
January 1993 Xia Y, Fertel RH, and Wood JD."Interactions of Biogenic Amines, Brain-Gut Peptides and Purine Nucleotides with Adenylate cyclase in Signal Transduction for Slow Synaptic Excitation (Slow EPSP) in Enteric Neurons" . : 225
January 1994 Xia Y, Fertel RH, and Wood JD."Endogenously Released Adenosine Acts at the A1 Receptor Subtype to Suppress Formation of Cyclic AMP in Myenteric Ganglia of Guinea-pig Small intestine in vitro" . : A851
January 1995 Xia Y, Zafirov DH, Cooke HJ, and Wood JD."Action of Tumor Necrosis Factor (TNF) on Electrical and Synaptic Behavior in the Submucous Plexus of Guinea-Pig Small Intestine" . : A945
January 1995 Xia Y, Peck OC, Cooke HJ, and Wood JD."Inflammatory Mediators Suppress Inhibitory Neurotransmission in Morphologically Identified Neurons in the Submucous Plexus of the Guinea-Pig Small Intestine" . : 293
January 1995 Xia Y, Zafirov DH, Mohanraj P, Cooke HJ, and Wood JD."Identification of Tachykinin Receptors on Neurons Identified Morphologically in the Myenteric and the Submucous Plexus of Guinea-Pig Small Intestine" . : A1017
January 1995 Wood JD, Zafirov DH, and Xia Y.."Daiichi DQ-2511 Facilitates Excitatory Processes and Suppresses Inhibitory Neuro-Transmission in the Enteric Nervous System of Guinea-Pig Small Intestine" . : A711
January 1996 Xia Y, Cooke HJ, and Wood JD."Interleukin-1 beta and Interleukin-6 Excite Neurons and Suppress Inhibitory Noradrenergic Neurotransmission Inflammatory Mediators Suppress Inhibitory Neurotransmission in the Submucous Plexus of Guinea-Pig Small Intestine" . : A783
January 1996 Xia Y, Gang L, Zafirov DH, Sarna SK, and Wood JD."Effects of Platelet-activating Factor on Electrical and Synaptic Behavior of Neurons in the Submucous Plexus of Guinea-Pig Small Intestine" . : A782
January 1997 Xia Y, Pothoulakis C, and Wood JD."Clostridium Difficile Toxin A Excites Enteric Neurons and Suppresses Inhibitory Noradrenergic Neurotransmission in Submucous Plexus of Guinea-Pig Small Intestine" .
January 1997 Wood JD, Xia Y.."Actions of Inflammatory Mediators on Electrical and Synaptic Behavior in the Submucous Plexus of Guinea-Pig Small Intestine" . : 1819
January 1997 Xia Y, Pothoulakis C, and Wood JD."Effects of Clostridium Difficile Toxin A on Electrical and Synaptic Behaviors in Submucous Plexus of Guinea-Pig Small Intestine" . : 255
January 1998 Wood JD, Xia Y, Hu H-Z.."Inhibition of Sympathetic Brake in the Enteric Nervous System" . : 1590
February 1998 Wood JD, Xia Y, Peck OC, and Pothoulakis C."Neuronal Mechanisms of Enterotoxin-Induced Power Propulsion and Diarrhea in the Colon" . : 109
April 1998 Hu H, Liu S, Xia Y, Mostafa R, Zafirov DH, and Wood JD."Actions of Bradykinin on Electrical and Synaptic Behaviors in the Myenteric and Submucous Plexuses of Guinea-Pig Small Intestine" . : A379
April 1999 Ren J, Hu H, Liu S, Xia Y, and Wood JD."Actions of Glutamate on Electrical and Synaptic Behaviors of the Submucous Plexuses Neurons in Guinea-Pig Small Intestine" . : G2857
April 1999 Hu H, Liu S, Ren J, Xia Y, and Wood JD."Actions of Prostaglandins on Electrical and Synaptic Behaviors of the Submucous Plexuses neurons in Guinea-Pig Small Intestine" . : G2856
September 1999 Xia Y, Tibbits D, Reilley T, and McSweeny T."Comparison of Effects of Lidocaine Hydrochroride, Cabonated Lidocaine, Diphenhydramine, and Normal Saline after Intradermal Injection" . : A466
September 2000 Xia Y Chen E, Reilley T, and McSweeny T."Effects of Lidocaine Hydrochloride, Carbonated Lidocaine, Diphenhydramine, and Normal Saline after Intradermal Injection" . : B10
April 2000 Liu S, Hu H, Ren J, Gao C, Xia Y, and Wood JD."Nociceptin Hyperpolarizes Neurons and Suppresses Synaptic Transmission in the Myenteric Plexus of Guinea-Pig Duodenum" . : A868
November 2000 Hu H, Gao N, Lin Z, Gao C, Liu S, Ren J, Xia Y and Wood JD.."Neurofilament 145 Immunoreactivity in Enteric Nervous System in Gunea Pig Small Intestine" . : 1680
April 2000 Wood JD, Xia Y, Hu H, Liu S, and Ren J."Actions of Glial Derived Neurotrophic Factor (GDNF) on Electrical and Synaptic Behavior of Enteric Neurons in Guinea-Pig Small Intestine" . : A150
September 2000 Kelly W, Xia Y, Harter R, Ralston BS, and Smith BS."Series O2 Configuration Enhances O2 Delivery" . : A661
April 2000 Hu H, Liu S,Xia Y, Ren J, Gao C, Peck OC and Wood JD."Histamine H3 Receptor-Mediated Suppression of Inhibitory Synaptic Transmission in the Submucous Plexus of Guinea-Pig Small Intestine" . : A431
September 2000 Xia Y, Chen E, Reilley T, and McSweeny T."Evaluation of Effects of Lidocaine Hydrochloride, Carbonated Lidocaine, Diphenhydramine, and Normal Saline after Intradermal Injection" . : A842
April 2001 Hu H, Gao N, Ren J, Liu S, Gao C,Xia Y and Wood JD."A Novel Metabotropic P2Y1 Receptor in the Submucous Plexus of Guinea-Pig Small Intestine." . : A509
April 2001 Gao N, Hu H, Liu S, Gao C, Xia Y and Wood JD."Adenosine 5-Monophosphate Activates Postsynaptic A2a Receptors and Presynaptic A1 Receptors on S-type Neurons in Guinea-Pig Ileal Submucous Plexus." . : A177
April 2001 Liu S, Hu H, Gao C, Gao N, Xia Y and Wood JD."Characterization of Leukotriene Actions on Enteric Neurons on the Guinea-Pig Small Intestine in vitro" . : A535
April 2001 Liu S, Hu H, Gao C, Gao N, Xia Y and Wood JD."Galaning Receptor-Mediated Inhibitor of Synaptic Transmission in the Submucous Plexus of Guinea-Pig Small Intestine" . : A509
April 2001 Gao C, Hu H, Liu S, Gao N, Xia Y and Wood JD."Effects of Stimulating Protease-Activated Receptors on Myenteric Neurons in Guinea-Pig small intestine" . : A176
October 2001 Hu H-Z, Lin Z, Ren J, Peck OC, Liu S, Gao C, Gao N, Xia Y and Wood JD."P2X7 Receptor in the Enteric Nervous System of Guinea-Pig Small Intestine" . : 399
October 2001 Hu H-Z, Gao N, Gao C, Liu S, Xia Y and Wood JD."Calmodulin (CaM) and CaM Kinase Signaling in the Enteric Nervous System." . : 11
October 2002 Wang G-D, Wang X-Y, Zhao Z-Q, Xia Y and Wood JD.."Primary A Fiber Neurons Mediate Nociceptive Synaptic Transmission in Adult Spinal Dorsal Horn of the Inflammatory" . : 8
April 2002 Hu H-Z, Gao N, Liu S, Wang GD, Wang XY, Fang X, Xia Y and Wood JD."Purinergic Interactions at the Interface between Sympathetic Postganglionic Neurons and Submucosal Plexus in Guinea Pig Small Intestine." . : A608
February 2002 Hu H-Z, Gao N, Zhu M, Liu S, Gao C, Xia Y and Wood JD."Purinergic Slow Excitatory Synaptic Transmission in Guinea Pig Small Intestinal Submucosal Plexus" . : A8
April 2002 Gao N, Wang X, Hu H-Z, Liu S, Wang G, Gao X, Kim G, Xia Y. , and Wood JD."Distribution of Neurofilament 200 in the Myenteric and Submucosal Plexus of Guinea Pig Small Intestine" . : A163
October 2002 Wood JD, Hu H, Gao N, Zhu M, Liu S, Gao X, Wang G, Wang X, and Xia Y."Transient Receptor potential Channel 6 in Guinea-Pig Small Intestinal Submucosal Plexus" . : 590-591
October 2002 Wang G-D, Hu H-Z, Gao N, Wang X-Y, Liu S, Xia Y, and Wood JD."Expression of Receptors for Angiotensin in the Enteric Nervous System of Guinea-Pig Small Intestine" . : 453
January 2003 Wood JD, Xia Y, Wang X, Wang G, Peck OC, Gao N, Liu S, and Hu H-Z.."Platelet Activating Factor (PAF) in the Enteric Nervous System of Guinea-Pig Small Intestine." . : 9
April 2003 Gao N, Hu H, Arlin SW, Cook CH, Needleman BJ, Muscarella P, Fang X, Xia Y and Wood JD.."Calmodulin Kinase II in the Signal Transduction Pathway for Slow Synaptic Excitation in Enteric Neurons of Guninea Pig Rat and Human Small Intestine." . : A467
April 2003 Liu S, Gao X, Gao N, Wang X, Hu H-Z, Scott SW, Wang G, Fang X, Xia Y, Wood JD."Expression of Receptors for Corticotropin-Releasing Factor in the Guinea-Pig Enteric Nervous System" .
July 2003 Hu H-Z, Gao N, Liu S, Fang X, Wang G,Xia Y, Wood JD."Signal Transduction for Purinergic P2Y1 Receptor-Mediated Slow EPSPs in Guinea-Pig Small Intestinal Submucosal Plexus" . : 218
July 2003 Liu S, Gao N, Wang X, Fang X, Gao X, Hu H-Z, Wang G, Arlin SW, Xia Y, Wood JD."Actions and Cellular Localization of Corticotropin-Releasing Factor in the Guinea-Pig Enteric Nervous System" . : 219
April 2004 Liu S, Hu H-Z, Gao N, Wang G-D, Wang X-Y, Fang X, Xia Y, Wood JD.."CRF1 Receptor Mediate Excitatory Actions of Urocortin on neurons in Guinea-Pig Small Intestinal Myenteric Plexus." . : A93
April 2004 Wang G-D, Hu H-Z, Wang X-Y, Gao N, Liu S, Fang X, Xia Y, Wood JD.."Purinergic Inhibitory Neuromuscular Transmission Mediated by the P2Y1 Receptor in Guinea-Pig Small Intestine." . : A275
April 2004 Xia Y, Wang X, Wang G, Liu S, Hu H-Z, Gao N, Fang X, and Wood JD.."Presynaptic μ-Opioid Receptors inhibit Release of Acetylcholine and ATP in Guinea-Pig Small Intestinal Submucosal Plexus." . : A11
April 2004 Fang X, Hu H-Z, Liu S, Wang G-D, Gao N, Wang X-Y, Xia Y, Wood JD."Neurogenic Mucosal Secretion Mediated by the Purinergic P2Y1 Receptor in Guinea-Pig Small Intestine." . : A148
April 2004 Gao N, Hu H-Z, Wang C, Liu S, Wang G-D, Wang X-Y, Fang X, Xia Y, Wood JD.."Trascient Receptor Potential Canonical 6 (trpc6) Channel in Guinea-Pig Enteric Neurons." . : A93
April 2005 Wang G, Wang X, Hu H-Z, Liu S, Gao N, Fang X, Xia Y, and Wood JD.."Serotonin Acts at Pre-Junctional 5-HT 1a Receptors To Suppress Purinergic Inhibitory Neurotransmission to the Circular Muscle in Guinea-Pig Small Intestine." . : A363
October 2005 Xia Y, Wang G, Wang X, Wood JD, and Zhao B.."The Effects of Mast Cell Degranulation on Neuroimmune Communication in Peripheral Terminals of Primary Afferent Neurons." .
April 2005 Liu S, Gao N, Wang X, Fang X, Hu H-Z, Wang G, Xia Y and Wood JD."Hyperpolarization-Activated, Cyclic Nucleotide-Gated Cation Channels in Enteric Neurons of Guinea-Pig and Rat Small Intestine." . : A363
April 2005 Xia Y, Wang X, Wang G, Hu H-Z, Liu S, Gao N, Fang X, and Wood JD."Receptors for Platelet Activating Factor in the Enteric Nervous System of Guinea-Pig Small Intestine" . : A363
April 2005 Wang X, Wang G, Liu S, Hu H-Z, Gao N, Fang X, Xia Y, and Wood JD."Calcitonin Gene-Related Peptide Signaling in the Enteric Nervous System of Guinea-Pig Small Intestine." . : A362
August 2005 Hu H-Z, Fang X, Liu S, Wang X, Gao N, Xia Y and Wood JD.."Actions of Tegaserod (HTF 919) in the Enteric Nervous System of Guinea-Pig Small Intestine." . : 614
August 2005 Fang X, Liu S, Wang X, Gao N, Hu H-Z, Wang G, Cook CH, Needleman BJ, Mikami DJ, Xia Y, and Wood, JD.."Serotonergic 5-HT4 Receptors in Guinea-Pig and Human Small Intestinal Enteric Nervous System and Mucosa." . : 614
April 2006 Liu S, Wang X, Fang X, Gao N, Gao C, Hu H-Z, Wang G, Xia Y, and Wood JD.."Endothelin Receptors and Actions in Adult Guinea-Pig Enteric Nervous System." . : A30
April 2006 Xia Y, Wang X, Wang G, Liu S, Gao N, Fei G, Hu H-Z, and Wood JD.."Activation of the Cholecystokinin-1 Receptor Subtype Attenuates Development of Desensitization of Opioid Receptors in Morphologically-Identified Myenteric S-Type Neurons in Guinea-Pig Small Intestine." . : A29
April 2006 Gao N, Hu H-Z, Fang X, Liu S, Fei G, Wang X-Y, Wang G-D, Xia Y, Wood JD."Expression of the Transient Receptor Potential Vanilloid 4 (TRPV4) Channel in the Enteric Nervous System of the Rat." . : A381
April 2006 Fei G, Fang X, Wang X, Wang G, Liu S, Gao N, Fei G, Hu H-Z, Xia Y, and Wood JD."Neurogenic Mucosal Bicarbonate Secretion Mediated by the Purinergic P2y1 Receptor in Guinea-Pig Duodenum." . : A380
September 2006 Xia Y, Reilley T, Gerhardt M, and McSweeny T.."Intrathecal Neostigmine for Knee Surgery Reduces Total Dose of Post-operative Analgesia." .
April 2006 Wang X, Wang G, Xia Y, Liu S, Gao N, Fei G, Hu H-Z, and Wood JD.."Characteristics of the Serotonergic (1A) Receptor Expressed by Mast Cells in Guinea-Pig Intestine." . : A379
April 2006 Wang G, Wang X, Liu S, Gao N, Fei G, Hu H-Z, Xia Y, and Wood JD.."Extrinsic Primary Afferent Neurons Stimulate Enteric Mast Cells to Release Histamine as a Paracrine Modulator in the Enteric Nervous System in the Guinea-Pig Intestine." . : A30
May 2007 Qu M, Hu H, Gao N, Wang G, Wang X, Fei G, Zou F, Du Y, Xia Y, Wood JD, and Liu S.."Synaptic Activation of Trpc Channels By Metabotropic Purinergic P2Y1 Receptors in the submucosal Plexus of the Guinea-pig Small Intestine." . : A18
September 2007 Xia Y, Wang G, Wang X, Liu S, Fei G, and Wood JD.."Sensitivity of Guinea-Pig Small Intestinal Spinal Afferents in Models for Food Allergy and Chemically-Induced Inflammation." . : 38
April 2007 Qu M, Wang X, Liu S, Wang G, Fei G, Zou F, Du Y, Xia Y and Wood JD.."Brandykinin-Induced Cyclooxygenase-2 Expression and Prostaglandin E2 Rlease in the Enteric Nervous System of Guinea-pig Small Intestine." . : A330
September 2007 Liu S, Qu M-H, Hu H-Z, Gao N, Wang G-D, Wang X-Y, Fei G, Zou F, Xia Y, and Wood JD.."Differential expression of TRPC channels in the guinea-pig enteric nervous system." . : 40
April 2007 Wang X, Wang G, Xia Y, Liu S, Fei G, Zou F, Du Y, Qu M, and Wood JD.."Enteric Mast Cells in Experimental Allergic and Non-Allergic Enterocolitis in Guinea-pigs." . : A332
September 2007 Fei G, Du Y, Wang X-Y, Zou F, Liu S, Qu M-H, Xia Y, Wang G-D, Wood JD.."Stimulation and inhibition of mucosal secretion by dopamine D1 and D2 receptors in the enteric nervous system (ENS) of guinea pig small intestine." . : 41
January 2007 Fei G, Liu S, Qu M-H, Wang G-D, Wang X-Y, Zou F, Xia Y, Bohn L, Wood JD.."Lubiprostone by passes morphine-induced inhibition of secretion in guinea pig intestine." . : 60
April 2007 Wang G, Wang X, Fei G, Liu S, Zou F, Du Y, Qu M, Xia Y and Wood JD.."Synaptic Behavior in the Enteric Nervous System (ENS) of Guinea-pigs with Experimentally-induced Enterocolitis or Food Allergy." . : A332
April 2007 Fei G, Liu S, Wang G, Qu M, Wang X, Zou F, Du Y, Xia Y, and Wood JD.."Stimulation of Mucosal Secretion by Lubiprostone in Guinea-pig Small intestine and Colon." . : A683
September 2007 Wang G-D, Wang X-Y, Liu S, Fei G,Xia Y, Wood JD.."Receptors for dopamine in the enteric nervous system of guinea pig small intestine." . : 41
November 2008 Wang X, Wood JD, Wang G, Zou F, Xia Y, Liu S, and Fei G.."Functional Expression of Dopamine Receptor Subtypes in the Guinea Pig Small Intestine Enteric Nervous System." .
May 2008 Liu S, Qu M, Ren W, Bhargava A, Chang J, Hoy JJ, Wang G, Zou F, Wang X, Sun X, Xia Y, and Wood JD.."Silencing of Gene Expression for Corticotropin-Releasing Factor (CRF) in the Colon Attenuates Stress-Induced Acceleration of Colonic Transit in Rats." .
April 2008 Qu M, Wang X, Sun X, Liu S, Wang G, Zou F, Xia Y and Wood JD.."Enteric Neurophysiological Mechanisms of Action for Bradykinin-Evoked Mucosal Chloride Secretion in Guinea Pig Small Intestine." .
April 2008 Xia Y, Wang X, Wang G, Zou F, Fei G, Liu S, Qu M, Sun X, Ren W, and Wood JD.."Dopamine D1 and D2 Receptor Subtypes Are Involved in Enteric Neural Control of Chloride and Bicarbonate Secretion in Guinea Pig Duodenum." .
November 2008 Wang G, Wood JD, Wang X, Xia Y, and Liu S.."Electrophysiological Plasticity of AH-type Neurons in the Enteric Nervous System of Normal and Inflamed Guinea Pig Small Intestine." .
April 2008 Wang G, Wang X, Zou F, Xia Y, Liu S, Qu M, Sun X, Ren W, and Wood JD.."Excitation of Neurons in the Enteric Nervous System (ENS), Degranulation of Enteric Mast Cells and Direct Action on Enterocytes Underlie Stimulatory Action of Bradykinin (BK) on Mucosal Secretion in Geuinea Pig Small Intestine." .
May 2008 Sun X, Xia Y, Wang Y, Qu M, Wang X, Wang G, Needleman B, Mikami D, Melvin WS, Bohn L, Ueno R, and Wood JD.."Lubiprostone Reverses the Inhibitory Action of Morphine in Mucosal Secretion in the Human Jejunum." .
May 2009 Qu M, Liu S, Ren W, Sun X, Wang X, Wang G, Baldassano S, Xia Y, Wood JD."Canonical Transient Receptor Potential Channels (TRPC Channels) in Regulation of Mucosal Chloride Secretion in Guinea Pig Lleum" . : A554
September 2009 Peralta F, Small RH, Xia Y.."Emergency Delivery of Twin Gestation Previously Scheduled for EXIT Procedure" .
May 2009 Baldassano S, Liu S, Qu M, Ren W, Wang X, Wang G, Xia Y, Wood JD."Activation of the Glucagon-Like Peptide-2 Receptor Inhibits Neurally-Evoked Mucosel Chloride Secretion in the Guinea Pig Lleum In Vitro" . : A-50
May 2009 Wang X, Wang G, Liu S, Qu M, Ren W, Baldassano S, Xia Y, Wood JD."Mast Cell Proteases Stimulate Neurogenic and Non-Neurogenic Mucosal Chloride Secreation in Guinea Pig Distal Lleum" . : A-554
June 2009 Wang G, Wang X, Zou F, Xia Y, Liu S, Qu M, Ren W, Wood JD."Stimulation of Spinal Afferents Evokes Slowly-Activating Excitatory Responses in Enteric Neurons in Parallel with Release of Mast Cell Proteases in Guinea Pig Lleum and Colon" . : A-19
July 2009 Wood JD, Wang G, Wang X, Liu S, Xia Y.."Interactive Signaling Between Spinal Afferents, Enteric Mast Cells and the Enteric Nervous System in Guinea Pig Intestine." .
May 2010 Xia Y, Wang X, Wang G-D, Needleman BJ, Mikam DJi Melvin WS, Wood JD.."Activating factor (PAF) Enhanced Secretion and Motility in Human Small Intestine." . : S622
May 2010 Wang X, Xia Y, Wang G-D, Needleman BJ, Mikam DJ, Melvin WS, Wood JD."Mast Cell Activation by Corticotropin Releasing Factor (CRF) in Guinea Pig and Human Intestine." . : S-620
May 2010 Wang G-D, Wang X, Xia Y, Needleman BJ, Mikam DJi Melvin WS, Wood JD."Stimulation of Intramural Spinal Afferents with Capsaicin Enhances Purinergic Inhibitory Neuromuscular Transmission in Human Jejunum." . : S-276
January 2011 Wang G-D, Wang X, Xia Y, Wood JD."Neurobiology and Neuropharmacology of the D2 Class of Dopaminergic Receptors in the Guinea Pig Enteric Nervous System (ENS)" .
October 2011 Yuratich D, Dzwonczyk R, and Xia Y."Emergency Delayed Epidural Catheter Migration into the Subarachnoid Space – A Rare but Serious Event" .
January 2011 Wang x, Wang G-D, Xia Y, Needleman BJ, Mikami DJ, Melvin WS, Wood JD."Dopaminergic Control of Mucosal Secretion in Human Small Intestine" .
January 2011 Wang X-y, Wang G-d, Xia Y and Wood JD."Endogenous capsaicin-like lipids in guinea pig and human small intestine" .
January 2011 Xia Y, Wang X, Wang G-D, Needleman BJ, Mikami DJ, Melvin WS, Wood JD."Lubiprostone Facilitates Cholinergic Neurogenic Mucosal Secretion in Guinea Pig and Human Small Intestine" .
January 2011 Wang X, Wang G-D, Xia Y, Needleman BJ, Mikami DJ, Melvin WS, Wood JD."Dopaminergic Control of Mucosal Secretion in Human Small Intestine" .
May 2012 ."" .
May 2012 Guo-Du Wang, Yun Xia, Xiyu Wang, Bradley Needleman, Dean J. Mikami, W.S. Melvin, Jackie D. Wood."Puringeric Inhibitory Neuromuscular Transmission in Human Jejunum and Guinea Pig Colon" .
May 2012 Guo-Du Wang, Xiyu Wang, Yun Xia, Dean J. Mikami, Bradley Needleman, W.S. Melvin, Jackie D. Wood."Dopaminergic Control of Motility in Human and Guinea Pig Intestine" .
April 2013 Xia Y, Hu P, Hu L, Stellaccio F, Xia T, and Dzwonczyk R.."Impact of No Pain Labor N' Delivery on labor analgesia rate and obstetric practice in a Chinese academic hospital" .
May 2013 Xia Y, Hu M, Hu L, Wong CA, Stellacio FS, Wang Y, Huang W, Li Y, Xia T, Dzwonczyk RR."Impact of Neuraxial Labor Analgesia on Oxytocin Augmentation and Postpartum Hemorrhage" . : A4056
May 2013 Wang X, Wang G, Qu M, Xia Y, Needleman BJ, Mikami DJ, Wood JD."Beta-Nicotinamide Adenine Dinucleotide (Beta-NAD) Acts at Inhibitory Adenosine A1 Receptors Expressed by Neurons in the Enteric Neural Circuits" . : S295
April 2014 Wang GD, Wang X, Xia Y, and Wood JD."Reversal of Opioid-Induced Constipation by Lubiprostone (Amitiza®) in Guinea Pig Ileum" . : S89
April 2015 Wood JD, Wang GD, Wang X, and Xia Y."Dopamine D1 and D2 Receptors Expressed by Musculomotor and Secretomotor Neurons in the Enteric Nervous System (ENS) and the Dorsal Vagal Motor Nucleus for Guinea Pig and Mouse" . : S-540
May 2015 Drzymalski DM, Palatrik A, Xia Y, Zhao Q, Qi X, Pian-Smith M."A Pilot Study of a High-Fidelity, Low-Cost, and Simulation-Based Educational Intervention to Improve Obstetric Patient Safety and Teamwork in China" . : F-20

Presentations

Biochemical Basis of Slow Excitatory Postsynaptic Potentials in Enteric Nervous System of Guinea-pig Small Intestine

Inflammatory Mediators Suppress Inhibitory Neurotransmission in Morphologically Identified Neurons in the Submucous Plexus of the Guinea-Pig Small Intestine

(1) Anesthesia and Gastrointestinal Function, and (2) Obstetrical Anesthesia in US.

A Brief Introduction to Acupuncture

Introduction to Acupuncture

Effects of Lidocaine Hydrochloride, Carbonated Lidocaine, Diphenhydramine, and Normal Saline after Intradermal Injection.

Parallel vs. Series: How Do I Back up My Oxygenator

Effects of C. Difficile Toxin A on Enteric Nervous System

Medical Pain Management in the Obstetrical Patient

Medical Pain Management in the Obstetrical Patient

Medical Pain Management in the Obstetrical Patient

Introduction to Labor and Delivery

Introduction to Labor and Delivery

OB Anesthesia Update

(1) Anesthesia and Gastrointestinal Function, and (2) Obstetrical Anesthesia in US.

Obstetric Anesthesia in the US

(1) Pre-operative Evaluation; (2) Obstetric Anesthesia in the US

Update of Practice Guideline of OB Anesthesia in US

(1) Conscious Sedaton; (2) Pre-Operative evaluation; (3) Anesthesia and gastrointestinal function

Obstetric Anesthesia in the US

Obstetric Anesthesia in the US

(1) Pre-op evaluation and Pre-op medication, (2) Conscious sedation, (3) Obstetrical anesthesia in US

Rational use of opioids

(1) Rational use of opioids; (2) ASA Practice Guidelines for Obstetrical Anesthesia; Rational use of opioids, (2) Practice guideline for obstetrical anesthesia, (3) Anesthetic Consideration for OB Patients with Thrombocytopenia

(1) Practice guideline for obstetrical anesthesia; (2) Anesthetic consideration for patients with Pre-eclampsia

(1) Introduction of OSUMC; (2) OB Anesthesia

Intrduction to OSUMC

(1) Introduction to OSUMC; (2) OB Anesthesia

(1) Introduction to OSUMC; (2) OB Anesthesia

Anesthetic consideration for OB patients with thrombocytopenia and coagulopathy.

(1) OB Anesthesia; (2) Chronic adhesive arachnoiditis and regional anesthesia; (3) Current Controversies in Critical Care

(1) Can OB anesthesia result in chronic adhesive arachnoiditis?; (2) Current Controversies in Critical Care

(1) Introduction to OSUMC; (2) OB Anesthesia

OB Anesthesia Update

1. Enteric Mast Cells in Experimental Allergic and Non-Allergic Enterocolitis in Guinea-pigs. Gastroenterology

(1) 2007 ASA Practice Guidelines for Obstetric Anesthesia; (2) Anesthetic consideration for OB patients with thrombocytopenia; (3) Anesthetic consideration for patients with Pre-eclampsia; (4) Regional anesthesia; (5) Current controversies in OB anesthesia; and (6) Introduction to OSUMC

What Is New in 2007 ASA Practice Guidelines for Obstetric Anesthesia?

Practice Guidelines for Acute Pain Management in the Perioperative Setting

Clinical Application of Opioids

Anesthetic considerations for parturients with cardiac diseases.

2007 ASA Practice Guidelines for OB Anesthesia

2007 ASA practice Guidelines for OB Anesthesia

2007 ASA Practical Guidelines for OB Anesthesia

(1) 2007 ASA Practice Guidelines for OB Anesthesia; (2) Personalized Medicine

Labor analgesia in the US

Clinical Application of Opioids

Anesthetic consideration of preeclampsia

Labor Analgesia

Labor Analgesia

Anesthetic considerations of a parturient with coagulopathy

Emergency Delivery of Twin Gestation Previously Scheduled for EXIT Procedure.

Anesthesia and GI function.

Update of OB Anesthesia in the U.S.

OB Anesthesia in the U.S.

Anesthetic Managements of A Parturient with Multiple Co-existing Diseases

(1) Update of labor analgesia in the U.S; (2) Anesthetic considerations of a parturient of multiple co-existing diseases

OB Anesthesia Update

Clinical Application of Opioids

Clinical Application of Opioids

Preeclampsia.

Clinical Application of Opioids

Clinical Application of Opioids

(1) Update of OB Anesthesia Practice Guidelines; (2) Preeclampsia

Ultrasound Guided Regional Anesthesia

Case discussion on OB anesthesia complication.

(1) Perioperative Managements; (2) Ultrasound guided Reginal Anesthesia

(1) Endoluminal Surgery, (2) Personalized Medicine, (3) Robot Surgery, and (4) Ultrasound Guided Regional Anesthesia.

(1) Endoluminal Surgery, (2) Personalized Medicine, (3) Robot Surgery,

(1) Endoluminal Surgery, (2) Personalized Medicine, (3) Robot Surgery

Perioperative Pain Managements

Perioperative Pain Managements

Health Care in China

Clinical Application of Opioids

OB Anesthesia complications

Update of Clinical Managments of Pre-eclampsia

Clinical Application of Opioids

1) Update of Pre-eclampsia, 2) Anesthetic Consideration of Thrombocytopenia, 3) Labor Analgesia

1) Update of Pre-eclampsia, 2) Anesthetic Consideration of Thrombocytopenia

Anesthesia Complications.

(1) Stimulation of Intramural Spinal Afferents with Capsaicin Enhances Purinergic Inhibitory Neuromuscular Transmission in Human Jejunum; (2) Mast Cell Activation by Corticotropin Releasing Factor (CRF) in Guinea Pig and Human Intestine; (3) Platelet Activating factor Enhanced Secretion and Motility in Human Small Intestine.

OB Anesthesia Managements

Perioperative Pain Managements

OB Anesthesia Update

OB Anesthesia

1) Update of Pre-eclampsia, 2) Anesthetic Consideration of Thrombocytopenia, 3) Labor Analgesia

(1) Acute Pain Managements; (2) Introduction to OSUMC; (3) OB Anesthesia; (4) Residency Training in the US

Delayed Epidural Catheter Migration into the Subarachnoid Space – A Rare but Serious Event

CASA Research Strength

Perioperitive Pain Managements

Perioperative Pain Managements

Perioperative Pain Managements

Anesthetic Managements of Upper GI Surgeries

Anesthetic Managements of A Parturient with Multiple Co-existing Diseases

OB Anesthesia Complications

Perioperative Pain Managements

Perioperative Pain Managements

Effects of Opioids on Gastrointestinal Functions

(1) Anesthetic Managements of Cesarean Section; (20 Managements of Acute Pain in Perioperitive Setting.

Perioperative Pain Managements

(1) OB Anesthesia; (2) Perioperative Pain Mangements

(1) Anesthetic Managements of Thrombocytopenia; (2)Anesthetic Management of a Parturient with multiple co-existing diseases

Managements of Neuronal Complications of OB Anesthesia

(1) Lubiprostone Facilitates Cholinerrgic Neurogenic Mucosal Secretion in Guinea Pig and Human Small Intestine; (2) Neurobiology and Neuropharmacology of the D2 Class of Dopaminergic Receptors in the Guinea Pig Enteric Nervous System; (3) Dopaminergic Control of Mucosal Secretion in Human Small Intestine

Perioperative Pain Managements

Perioperative Pain Managements

Perioperative Anesthetic Managements

Improving Safety of OB Anesthesia

Improving Safety of OB Anesthesia

Improiving Safety of OB Anesthesia

Perioperative Pain Managements

Obstetric Anesthesia

Improving Obstetric Anesthesia

(1) Anesthesiology Residency Training in the US; (2) Perioperative Anesthetic Managements

Autoimmune Enteric Neuropathy

Improving Safety of Obstetric Anesthesia

Anesthetic Managements of Perioperative neurological Complications, Acute Pain, Marfan's Syndrome and Update Obstetric Anesthesia

Improving Safety of OB anesthesia, Clinical Applications of Opioids, Anesthesiology Residency Training in the Anesthesiology in the US, Autoimmune Enteric Neuropathy

Improving Safety of OB anesthesia, Clinical Applications of Opioids, Anesthesia Consideration of Perinatal Neurological Complications, and Update HELLP Syndrome

Anesthetic Managements of Perioperative Neurological Complications

Improving Safety of OB Anesthesia, Clinical Applications of Opiods, Anesthesiology Residency Training in the US, Autoimmune Enteric Neuropathy

(1) Update HELLP Syndrome, (2) Opioid receptors

Impact of Neuraxial Labor Analgesia on Oxytocin Augmentation and Postpartum Hemorrhage

Update Oxytocin Application during Obstetric Anesthesia

Perioperative Pain Managements

ICAA Symposium

Perioperative Pain Managements

Obstetric Anesthesia Safety

Perioperative Resource Managements

Update of Labor Analgesia in the US

Impact of Neuraxial Labor Analgesia on Oxytocin Augmentation and Postpartum Hemorrhage-A Report from No Pain Labor N' Delivery-GHI in China

Anesthetics & Regional Anesthesia, Quality Managements in OR, Acute Pain Managements

Difficult Airway in Obstetric Anesthesia

Oxytocin in OB Anesthesia, Acute Pain Management, Anesthetic Managements of Perinatal Neuronal Complications, Quality Managements in OR

Oxytocin in OB Anesthesia, Acute Pain Management

Managements of Difficult Airway

CRM in Hospital Mangements

CRM in Hospital Mangements

Acute Pain Managements

CRM in Hospital Mangements

Acute Pain Managements

Oxytocin in OB Anesthesia

CRM in Medical Practice

Anesthetic Managements of Difficult airway

Acute Pain Managements

Acute Pain Managements

Update of Obstetric Anesthesia

Residency Training in the US

Anesthetic Considerations of Parturient with Difficult Airway

Quality Control in Anesthesia

Pain Managements in Perioperative Setting

Anesthetic Managements of Laparoptic Surgery

Safety of Patient Care

Pain Managements in Perioperative Setting

Pain Managements in Perioperative Setting

Anesthetic Managements of Obese Parturients

Parioperative Pain Managements

Update of Obstetric Anesthesia

Medical Resource Managements

Anesthetic Managements of Obese Parturients

CRM in Medical Practice

Anesthetic Managements of A parturient with Multiple Co-Existing Diseases

Effective Leadership

Update of Obstetric Anesthesia

Update of Obstetric Anesthesia

Update of Obstetric Anesthesia

Perioperative Managements

Perioperative Managements

Update of Obstetric Anesthesia

Perioperative managements

Anesthesia out of Operation Rooms

Inhalational Anesthesia

Medical CRM

Inhalational Anesthesia

Obstetric Anesthesia

Anesthetic Managements of Perinatal Neuronal Complication

Receptors for platelet activating factor in the enteric nervous system of guinea-pig small intestine

INTERRELATIONS OF INHIBITORY ADENOSINE-A1-RECEPTORS, MEDIATORS OF SLOW SYNAPTIC EXCITATION (SLOW EPSP) AND ADENYLATE-CYCLASE IN THE MYENTERIC PLEXUS OF GUINEA-PIG SMALL-INTESTINE

ENDOGENOUSLY RELEASED ADENOSINE ACTS AT THE A1 RECEPTOR SUBTYPE TO SUPPRESS FORMATION OF CYCLIC-AMP IN MYENTERIC GANGLIA OF GUINEA-PIG SMALL-INTESTINE IN-VITRO

IDENTIFICATION OF TACHYKININ RECEPTORS ON NEURONS IDENTIFIED MORPHOLOGICALLY IN THE MYENTERIC AND SUBMUCOUS PLEXUSES OF GUINEA-PIG SMALL-INTESTINE

ACTIONS OF TUMOR-NECROSIS-FACTOR (TNF-ALPHA) ON ELECTRICAL AND SYNAPTIC BEHAVIOR IN THE SUBMUCOUS PLEXUS OF GUINEA-PIG SMALL-INTESTINE

Clostridium difficile toxin excites enteric neurons and suppresses inhibitory noradrenergic neurotransmission in the submucous plexus of guinea-pig small intestine.

Activation of the cholecystokinin-1 receptor subtype attenuates development of desensitization of opioid receptors in morphologically-identified myenteric S-type neurons in guinea-pig small intestine

Presynaptic mu-opioid receptors inhibit release of acetylcholine and ATP in guinea-pig small intestinal submucosal plexus

 

Professional Activities

0 A mission trip to developing countries to perform total hip and knee replacements. Operation Walk.
0 Traditional Chinese Medicine. The Ohio State Medical Center Summer Education Program. Columbus, OH.
0 International Medical Mission. No Pain Labor N' Delivery.
0 International Medical Mission. No Pain Lablor N' Delivery.
0 International Medical Mission. No Pain Labor N' Delivery.
0 International Medical Mission. No Pain Labor N' Delivery.
0 International Medical Mission. No Pain Labor N' Delivery.
1989 - 1993 Tutoring Students. The Ohio State University; Physiology 601 and 602 classes. Columbus, OH.
2007 - 2010 Advisor. OSU Chinese Student and Scholar Society.
 

Unpublished Works

Delayed Migration of an Epidural Catheter into the Subarachnoid Space- A Rare But Serious Event